OpenEvidence

OpenEvidence is used by about 650,000 active U.S. physicians and has reached tens of millions of clinical consultations per month across thousands of hospitals and medical centers.

OpenEvidence is used by about 650,000 active U.S. physicians and has reached tens of millions of clinical consultations per month across thousands of hospitals and medical centers.

OpenEvidence reported 18 million clinical consultations from verified U.S. healthcare professionals in December 2025, up from roughly 3 million monthly searches a year earlier, demonstrating rapid physician adoption at national scale.

OpenEvidence announced DeepConsult in July 2025: medically specialized reasoning agents analyze and cross-reference peer-reviewed studies in parallel and return a longer research synthesis, distinct from its rapid point-of-care search.

OpenEvidence develops clinical-search and evidence-synthesis systems grounded in licensed medical literature and medical-society partnerships.

OpenEvidence develops clinical-search and evidence-synthesis systems grounded in licensed medical literature and medical-society partnerships.

OpenEvidence has scaled a large U.S. physician network, major content partnerships, HIPAA/SOC 2 controls and multi-billion-dollar financing/valuation.

OpenEvidence has scaled a large U.S. physician network, major content partnerships, HIPAA/SOC 2 controls and multi-billion-dollar financing/valuation.

OpenEvidence raised $250M in Series D funding at a $12B valuation, bringing total funding to about $700M, and reported revenue above $100M; investors include Thrive, DST, Sequoia, Nvidia, Kleiner Perkins, Blackstone, BOND, Craft and Mayo Clinic.

OpenEvidence's engineering posting describes scaling backend services and data platforms with responsibility for reliability, performance, security and infrastructure for sensitive medical data.

LLM, retrieval and evidence-synthesis skills transfer broadly, but clinical knowledge, medical content and regulated-healthcare context materially constrain portability.

LLM, retrieval and evidence-synthesis skills transfer broadly, but clinical knowledge, medical content and regulated-healthcare context materially constrain portability.